User blog comment:Cinder23/What is the best perk set up?/@comment-1913186-20100425193218

Scavenger, Cold-blooded, and Ninja. It allows one to play stand-alone without having to worry about performance of his allies (in the case of enemies utilizing killstreaks) as well as emptying ammunition capacity. To accompany this set up, an Assault Rifle(like the M4A1, FAMAS, ACR, and few others) is best as well as Claymores. If mobile then Semtex.

In the case of objective matches when you want to end it fast or scramble and frustrate the opponents Marathon, Lightweight, and Steady Aim or Commando (SA or superknife is dependent on both your primary and secondary).

Both are about as "best" imho.