Apothicon

The Apothicons, according to Dr. Monty, are "the most powerful and evil entities in all of the existences that ever existed". The Shadow Man is a known Apothicon. Many weapons, such as the Apothicon Servant and Apothicon Swords are named after them.

In the Revelations opening cutscene, Maxis uses the Summoning Key, which accidentally summons the Shadow Man, who in turn summons the Apothicons.