The F-15 appears in Modern Warfare 3's Multiplayer as the Assault Package's 6-point reward, the Precision Airstrike. Much like its predecessor, three planes will fly in a straight direction of the spot where it is launched by the player who called it and drop their payloads. Getting a Game Winning Killcam with this earns the winner the "Finishing Touch" Challenge and 2500exp. Killing 5 enemies at once will earn the "Carpet Bomb" Challenge and 5000 exp. Calling in two Airstrikes in a single match will earn the "Afterburner" Challenge with 2500exp. While in Prestige, getting a certain number of kills will earn the "Carpet Bomber" Challenge of different levels.
The Precision Airstrike compliments well with the Predator Missile and the Attack Helicopter as a 5-6-7 Point Streak combo. With Hardline Pro, the two-assist-kill ability makes it much faster to achieve the combo in 4 points. Land a kill with the Predator Missile to earn the Airstrike. Call it in on a high traffic area to get your 6th point to earn the Helicopter, then call the chopper to gain additional kills as it flies around the map.
The F-15 makes a single appearance in the level The Hunted, where four F-15s escort the Y-8 gunship that extracts Rorke from the Ghosts' plane.
On the map Showtime, F-15s are the jets used to drop the care packages when the Slot Machine care package or the "jackpot" icon is chosen.
Call of Duty: Modern Warfare 2
All F-15s in the game bear the tail code "IW4" on their vertical stabilizers. The code usually identifies a plane's unit or base assignment, but since "IW4" is not in use by any of those entities, it clearly refers to the game's engine.