Some loadouts in standard Gunfight will include the Fists as a secondary weapon. In Gunfight: OSP, Fists serve as each player's starting weapon until another weapon is equipped. They can be switched back to until a second weapon is picked up.
In Battle Royale, everyone will begin with an X16 and the Fists. The first weapon picked up will always replace the Fists regardless of which weapon the player was holding. The Fists are also available in the Gulag, both while watching other fights and while participating in one.