Stukas appear in multiple missions in this game. Their first appearance was in "We've Been Through Worse", where a few of them do bombing runs on American positions. Their first appearance chronologically is in "Baptism By Fire". While clearing out the four hangars, multiple Stukas can be seen. In the second hangar, one will attempt to take off, but can be easily destroyed by using the MG42. While heading to a hanger to the other side of the one the player was, a stuka will attempt to kill the player, but fail due to an american fighter plane shooting is down. At the end of the mission, the player will be told to get on a Flakvierling to shoot down the Stukas. Once five or more are destroyed, the mission will end. Their next major appearance is in "Piano Lupo". The player is told to get on the half-track with the quad M2 Browning and defend the fuel supplies and American howitzers from the multiple attacking Stukas. A Stuka is seen crashed on the base of the hill the howitzwers are situated at. While shooting at some italians on the otherside of the hill, if the player look left, a Stuka is seen with smoke on it tail crashing on the italian side of the hill. Later in the mission, Stukas will perform bombing runs on American infantry. Stukas also appear in the missions "Tankers" and "An Easy Detail".
The Stuka appears in the mission "Mayenne Bridge" where while McCullin is defusing the first bomb a Stuka overhead is being chased by a Thunderbolt, going around the bridge before being hit on the right wing and crashing on a bell tower on the right side of the bridge. It also apper twice on the mission "The Crossroads". At one stage in the mission, a Stuka crashes into the building Nichols and his team are in, possibly shot down by a Thunderbolt. If the player head to the main road to destroy the Flakvierling a Stuka will apper to do a strafing run when the player get near the destroyed car in the middle of the road.
The Stuka appears in some various levels in Call of Duty: Roads to Victory. This fighter appears in Altavilla, Scavenger Hunt, Glider Crash, Sloedam, and Reichswald (the player can see two Stukas in the sky. The first is being chased by a British Spitfire while the other crashes on the ground above the player).
The Stuka appears in every mission of Call of Duty: WWII. It is the main aircraft the Luftwaffe uses throughout the campaign. Stukas can be seen attacking ground forces in most missions. A large number of them appears in the levels "Operation Cobra" and "The Rhine" as the player is tasked to destroy them with a Flak 38 .20 AA Gun mounted on a Sd. Kfz. 10 half-track. Stukas can also be seen unused in the level "Ambush", as the player infiltrates the German Air Base. The Stuka is also the model for the Fighter Pilot scorestreak in multiplayer for the Axis.
In the Nazi Zombies map The Darkest Shore, Stukas appear as enemies during a segment of the map's story quest, in which the players have to shoot them down using flak cannons positioned near the Artillery Bunker.