The Mk 22 Mod 0 is a silenced semi-automatic handgun in Call of Duty: Black Ops (Nintendo DS). It is the Allied side arm of choice and always has a silencer on it making for silenced kills. The Mk 22 is the secondary weapon in every SOG mission and can kill with two shots at close ranges or three to five if the target is far away. It has an eight round magazine and relatively fast reload. In Multiplayer it is unlocked from the start for the Allied faction. Getting 150 kills with the Mk 22 will unlock the M10. The Mk 22 is also used when in Last Stand. It appears in Zombies mode, but only when the player is downed.
- In the mission "Cold Feet", when parachuting in the Soviet base one hand will hold the Mk 22, the other will hold on the parachute. However shooting and then reloading will make a third hand appear and insert a fresh magazine.