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Reflex is a Handling Perk introduced in Call of Duty: Ghosts. It allows the player to swap weapons and use equipment faster, much like Sleight of Hand Pro and Quickdraw Pro from Call of Duty: Modern Warfare 3 and Fast Hands from Call of Duty: Black Ops II.
This perk can be incredibly useful when combined with Overkill as the player can quickly switch to a Shotgun and win CQC battles easier. Another use could be with a sniper class, as the player could also quickly switch to his/her secondary to take out players getting too close.