Spikers have red glowing eyes, making them similar in appearance to the Charger zombies, except that they have a large amount of spikes that course throughout their body and arms.
When shot in the torso, they will spread shrapnel around themselves, similar to the Spikemore from Call of Duty: Black Ops. The shrapnel can damage players as well as zombies who are close to the Spiker. Head shots are advised against Spikers to prevent spikes from shooting off.
One should be careful throwing a Nano Swarm at one, because the continuous damage will shoot off spikes at a faster rate and the shrapnel can easily kill the player, even when equipped with Exo Health.
In early rounds, Spikers will run at a moderate speed, and should thus be prioritized. Players who see a Spiker should stay away from it, and let it gather with a group of other zombies, which makes it effective upon death as it will injure other zombies.